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Data source: VAERS (Vaccine Adverse Event Reporting System)

Data through 2026 · Updated quarterly

Built by TheDataProject.ai · © 2026 VaccineWatch

Important: VAERS accepts reports of adverse events following vaccination. For any given report, there is no certainty that the reported event was caused by the vaccine. Reports may contain information that is incomplete, inaccurate, coincidental, or unverifiable. Most reports to VAERS are voluntary, which means they are subject to biases. This data cannot be used to determine if vaccines cause or contribute to adverse events.

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Important: VAERS reports alone cannot determine if a vaccine caused an adverse event. Reports may contain incomplete, inaccurate, or unverified information. Correlation does not equal causation.

  1. Home
  2. Vaccine Side Effects
  3. Polio Vaccine
5 min read
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Polio Vaccine Side Effects

The polio vaccine is one of the greatest public health achievements in history, virtually eliminating polio in the developed world. VAERS tracks adverse events for both the current inactivated vaccine (IPV) and the historical oral vaccine (OPV).

71,449
Total Reports
2,511
Deaths Reported
7,798
Hospitalizations
2
Vaccine Types

Most Reported Side Effects

#1Pyrexia
10,468
#2Injection site erythema
10,096
#3Erythema
5,283
#4Injection site swelling
5,190
#5Vomiting
4,020
#6Injection site warmth
3,823
#7Injection site oedema
3,736
#8Rash
3,397
#9Urticaria
3,312
#10Convulsion
3,005
#11Injection site pain
2,744
#12Injection site induration
2,514

IPV vs OPV

  • IPV (Inactivated Polio Vaccine / IPOL): Current standard in the U.S. — given by injection, contains killed virus. Cannot cause polio.
  • OPV (Oral Polio Vaccine): Historical — given by mouth, contains weakened live virus. No longer used in the U.S. since 2000 due to extremely rare cases of vaccine-derived polio.

Important context: most IPV VAERS reports are from combination vaccines (like DTaP-IPV) where the polio component is given alongside other antigens. Side effects may be from the combination rather than the polio component specifically.

Expected Side Effects (IPV)

Common:

  • Soreness and redness at injection site
  • Low-grade fever
  • Fussiness (in infants)

IPV is considered one of the safest vaccines. Serious adverse events directly attributable to IPV are extremely rare.

Historical Context: VAPP

The oral polio vaccine (OPV) carried a very small risk of vaccine-associated paralytic polio (VAPP) — about 1 case per 2.4 million doses. This is why the U.S. switched exclusively to IPV in 2000. OPV is still used in some countries for its ability to provide intestinal immunity and stop wild poliovirus transmission.

Explore This Data

IPV Detail →
Full VAERS profile
Pediatric Analysis →
Childhood vaccine data
All Side Effects →
Complete guide

More Side Effect Guides

DTaP Side Effects
Given at same visits as IPV
Rotavirus Side Effects
Another infant vaccine
MMR Side Effects
Measles, mumps, rubella