Important: VAERS reports alone cannot determine if a vaccine caused an adverse event. Reports may contain incomplete, inaccurate, or unverified information. Correlation does not equal causation.
Angioedema appears in 2,167 VAERS reports across all vaccines. Of these, 7 reports also mentioned death and 316 involved hospitalization. The severity rate (deaths + hospitalizations as a percentage of reports) is 14.9%. The top vaccines associated with this symptom are COVID-19, Flu (Trivalent), Shingles (Zostavax). Remember: VAERS reports show temporal association, not causation.
Angioedema has been reported 2,167 times in VAERS from 1990 to 2026.
Of these reports, 7 were associated with death (0.32%) and 316 involved hospitalization.
The overall serious outcome rate (death or hospitalization) for reports mentioning Angioedema is 14.9%.
This data comes from the Vaccine Adverse Event Reporting System (VAERS), jointly managed by CDC and FDA.