Important: VAERS reports alone cannot determine if a vaccine caused an adverse event. Reports may contain incomplete, inaccurate, or unverified information. Correlation does not equal causation.
Drug ineffective appears in 29,868 VAERS reports across all vaccines. Of these, 212 reports also mentioned death and 1,230 involved hospitalization. The severity rate (deaths + hospitalizations as a percentage of reports) is 4.8%. The top vaccines associated with this symptom are COVID-19, Chickenpox (Varivax), Hepatitis B. Remember: VAERS reports show temporal association, not causation.
Drug ineffective has been reported 29,868 times in VAERS from 1990 to 2026.
Of these reports, 212 were associated with death (0.71%) and 1,230 involved hospitalization.
The overall serious outcome rate (death or hospitalization) for reports mentioning Drug ineffective is 4.8%.
This data comes from the Vaccine Adverse Event Reporting System (VAERS), jointly managed by CDC and FDA.