Important: VAERS reports alone cannot determine if a vaccine caused an adverse event. Reports may contain incomplete, inaccurate, or unverified information. Correlation does not equal causation.
Fatigue appears in 181,355 VAERS reports across all vaccines. Of these, 1,336 reports also mentioned death and 10,540 involved hospitalization. The severity rate (deaths + hospitalizations as a percentage of reports) is 6.5%. The top vaccines associated with this symptom are COVID19, VARZOS, FLU3. Remember: VAERS reports show temporal association, not causation.
Fatigue has been reported 181,355 times in VAERS from 1990 to 2026.
Of these reports, 1,336 were associated with death (0.74%) and 10,540 involved hospitalization.
The overall serious outcome rate (death or hospitalization) for reports mentioning Fatigue is 6.5%.
This data comes from the Vaccine Adverse Event Reporting System (VAERS), jointly managed by CDC and FDA.