Important: VAERS reports alone cannot determine if a vaccine caused an adverse event. Reports may contain incomplete, inaccurate, or unverified information. Correlation does not equal causation.
Injection site pain appears in 134,294 VAERS reports across all vaccines. Of these, 125 reports also mentioned death and 2,235 involved hospitalization. The severity rate (deaths + hospitalizations as a percentage of reports) is 1.8%. The top vaccines associated with this symptom are COVID-19, Shingles (Zostavax), Pneumococcal (PPV23). Remember: VAERS reports show temporal association, not causation.
Injection site pain has been reported 134,294 times in VAERS from 1990 to 2026.
Of these reports, 125 were associated with death (0.09%) and 2,235 involved hospitalization.
The overall serious outcome rate (death or hospitalization) for reports mentioning Injection site pain is 1.8%.
This data comes from the Vaccine Adverse Event Reporting System (VAERS), jointly managed by CDC and FDA.