Important: VAERS reports alone cannot determine if a vaccine caused an adverse event. Reports may contain incomplete, inaccurate, or unverified information. Correlation does not equal causation.
Irritability appears in 10,844 VAERS reports across all vaccines. Of these, 163 reports also mentioned death and 1,285 involved hospitalization. The severity rate (deaths + hospitalizations as a percentage of reports) is 13.4%. The top vaccines associated with this symptom are HIBV, DTAP, PNC. Remember: VAERS reports show temporal association, not causation.
Irritability has been reported 10,844 times in VAERS from 1990 to 2026.
Of these reports, 163 were associated with death (1.50%) and 1,285 involved hospitalization.
The overall serious outcome rate (death or hospitalization) for reports mentioning Irritability is 13.4%.
This data comes from the Vaccine Adverse Event Reporting System (VAERS), jointly managed by CDC and FDA.