Important: VAERS reports alone cannot determine if a vaccine caused an adverse event. Reports may contain incomplete, inaccurate, or unverified information. Correlation does not equal causation.
Peripheral swelling appears in 40,006 VAERS reports across all vaccines. Of these, 164 reports also mentioned death and 2,129 involved hospitalization. The severity rate (deaths + hospitalizations as a percentage of reports) is 5.7%. The top vaccines associated with this symptom are COVID19, PPV, VARZOS. Remember: VAERS reports show temporal association, not causation.
Peripheral swelling has been reported 40,006 times in VAERS from 1990 to 2026.
Of these reports, 164 were associated with death (0.41%) and 2,129 involved hospitalization.
The overall serious outcome rate (death or hospitalization) for reports mentioning Peripheral swelling is 5.7%.
This data comes from the Vaccine Adverse Event Reporting System (VAERS), jointly managed by CDC and FDA.